Löffler , Friedrich August Johannes
(1852–1915) German bacteriologist
Löffler was born at Frankfurt in Germany, the son of an army surgeon. He was educated at the University of Würzburg and the Berlin Institute of Military Medicine, where – after serving in the Franco–Prussian War – he obtained his MD in 1874. After various official positions Löffler worked with Georg Gaffky as an assistant to Robert Koch from 1884 to 1888. He later served as professor of hygiene at the University of Griefswald (1888–1913), after which he succeeded Gaffky as director of the Koch Institute in Berlin, where he remained until his death.
Löffler's major contribution to the new field of bacteriology was the isolation and cultivation in 1884 of the bacillus responsible for diphtheria, which had first been observed by the German physiologist Theodor Klebs in the throats of diphtheria patients (the organism became known as the Klebs–Löffler bacillus). The isolation and cultivation of pure cultures involved a number of formidable technical problems; Löffler found it necessary to develop a new medium, thickened serum, as the conventional gelatin used by Koch required temperatures far too low for the diphtheria pathogen.
Earlier (in 1882) Löffler had discovered the organism responsible for glanders (a contagious disease, especially of horses) and in 1898, in collaboration with the pathologist Paul Frosch, he succeeded in demonstrating for the first time that viruses could cause diseases in animals. This was achieved by passing foot-and-mouth disease from one cow to another by inoculation with cell-free filtrates taken from lesions. Löffler's work, together with Dmitri Ivanovsky's demonstration in 1892 that plants were susceptible to viral infections, constituted the start of modern virology.

Scientists. . 2011.

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  • Löffler, Friedrich August Johannes — ▪ German bacteriologist born June 24, 1852, Frankfurt an der Oder, Prussia [Germany] died April 9, 1915, Berlin       German bacteriologist who, with Edwin Klebs (Klebs, Edwin), in 1884 discovered the organism that causes diphtheria,… …   Universalium

  • Löffler, Friedrich (August Johannes) — born June 24, 1852, Frankfurt an der Oder, Prussia died April 9, 1915, Berlin, Ger. German bacteriologist. In 1884, with Edwin Klebs (1834–1913), he discovered the organism that causes diphtheria. Simultaneously with Émile Roux (1853–1933) and… …   Universalium

  • Löffler, Friedrich (August Johannes) — (24 jun. 1852, Francfort del Oder, Prusia–9 abr. 1915, Berlín, Alemania). Bacteriólogo alemán. En 1884, junto con Edwin Klebs (1834–1913), descubrió el organismo que causa la difteria. Simultáneamente con Émile Roux (1853–1933) y Alexandre Yersin …   Enciclopedia Universal

  • Friedrich August Johannes Loffler — n. (1852 1915) German bacteriologist …   English contemporary dictionary

  • Friedrich Loffler — Friedrich Löffler Pour les articles homonymes, voir Löffler. Friedrich August Johannes Loeffler Friedrich August Johannes Loeffler (né le 24 juin 185 …   Wikipédia en Français

  • Friedrich Loeffler — Friedrich Löffler Pour les articles homonymes, voir Löffler. Friedrich August Johannes Loeffler Friedrich August Johannes Loeffler (né le 24 juin 185 …   Wikipédia en Français

  • Friedrich Löffler — Pour les articles homonymes, voir Löffler. Friedrich August Johannes Loeffler Friedrich August Johannes Loeffler (né le 24 juin 1852 à Francfort sur l Oder, décédé le …   Wikipédia en Français

  • Friedrich — /free drik/; Ger. /frddee drddikh/, n. a male given name. * * * (as used in expressions) Friedrich Leopold Baron von Hardenberg Baeyer Johann Friedrich Wilhelm Adolf von Beilstein Friedrich Konrad Benz Karl Friedrich Bernhardi Friedrich von… …   Universalium

  • Friedrich — (as used in expressions) Baeyer, (Johann Friedrich Wilhelm) Adolf von Beilstein, Friedrich Konrad Benz, Karl (Friedrich) Bernhardi, Friedrich von Bessel, Friedrich Wilhelm Beust, Friedrich Ferdinand, conde von Eugen Berthold Friedrich Brecht… …   Enciclopedia Universal

  • august — augustly, adv. augustness, n. /aw gust /, adj. 1. inspiring reverence or admiration; of supreme dignity or grandeur; majestic: an august performance of a religious drama. 2. venerable; eminent: an august personage. [1655 65; < L augustus sacred,… …   Universalium

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