Kendrew , Sir John Cowdery
(1917–1997) British biochemist
Kendrew, who was born at Oxford, graduated in natural science from Cambridge University in 1939. He spent the war years working for the Ministry of Aircraft Production, becoming an honorary wing commander in 1944. In 1946 he joined Max Perutzat Cambridge and, like Perutz, used x-ray diffraction techniques to study the crystalline structure of proteins, particularly that of the muscle protein myoglobin. X-ray diffraction, or crystallography, involves placing a crystal in front of a photographic plate and rotating the crystal in a beam of x-rays. The pattern of dots that is formed on the plate by the x-rays can be analyzed to find the positions of the atoms in the crystal. The technique had been used successfully to show the structures of small molecules but Kendrew's progress with the much larger myoglobin structure was slow, especially since diffraction patterns yield no information on the phases of the directed x-rays. However, in 1953 Perutz made a breakthrough by incorporating atoms of heavy elements into the protein crystals. Kendrew modified this new method and applied it successfully in his myoglobin studies, so that four years later he had built up a rough model of the three-dimensional structure of myoglobin. By 1959 he had greatly clarified the structure and could pinpoint most of the atoms.
Kendrew and Perutz received the 1962 Nobel Prize for chemistry for their work on protein structure. Kendrew was knighted in 1974 and served as director general of the European Molecular Biology Laboratory in Heidelberg from 1975 to 1982.

Scientists. . 2011.

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  • Kendrew,Sir John Cowdery — Ken·drew (kĕnʹdro͞o ), Sir John Cowdery. 1917 1997. British biologist. He shared the 1962 Nobel Prize for chemistry for determining the molecular structure of blood components. * * * …   Universalium

  • Kendrew, Sir John Cowdery — born March 24, 1917, Oxford, Oxfordshire, Eng. died Aug. 23, 1997, Cambridge, Cambridgeshire British biochemist. He received his Ph.D. from the University of Cambridge and as a Cambridge fellow (1947–75) went on to study the structure of proteins …   Universalium

  • Kendrew, Sir John Cowdery — (24 mar. 1917, Oxford, Oxfordshire, Inglaterra–23 ago. 1997, Cambridge, Cambridgeshire). Bioquímico británico. Obtuvo su Ph.D. en la Universidad de Cambridge y como miembro de ella (1947–75) se dedicó a estudiar la estructura de las proteínas.… …   Enciclopedia Universal

  • Sir John Cowdery Kendrew — noun English biologist noted for studies of the molecular structure of blood components (born in 1917) • Syn: ↑Kendrew • Instance Hypernyms: ↑biologist, ↑life scientist …   Useful english dictionary

  • John Cowdery Kendrew — John Cowdery Kendrew. Sir John Cowdery Kendrew (* 24. März 1917 in Oxford; † 23. August 1997 in Cambridge) war ein britischer Biochemiker und Molekularbiologe. Er erhielt 1962 gemeinsam mit Max Ferdinand Perutz den Nobelpreis für Chemie. Sein… …   Deutsch Wikipedia

  • John Cowdery Kendrew — John Kendrew John Kendrew Sir John Cowdery Kendrew (né le 24 mars 1917 à Oxford et mort le 23 août 1997 à Cambridge), était un biochimiste britannique. Il obtint en 1962, avec Max Ferdinand Perutz, le prix Nobel de chimie …   Wikipédia en Français

  • Chemienobelpreis 1962: John Cowdery Kendrew — Max Ferdinand Perutz —   Die beiden britischen Chemiker erhielten den Nobelpreis für ihre Studien über Strukturen globulärer Proteine.    Biografien   Sir (seit 1974) John Cowdery Kendrew, * Oxford (England) 24. 3. 1917, ✝ Cambridge 23. 8. 1997; 1959 …   Universal-Lexikon

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  • John C. Kendrew — John Cowdery Kendrew. Sir John Cowdery Kendrew (* 24. März 1917 in Oxford; † 23. August 1997 in Cambridge) war ein britischer Biochemiker und Molekularbiologe. Er erhielt 1962 gemeinsam mit Max Ferdinand Perutz den Nobelpreis für Chemie. Sein… …   Deutsch Wikipedia

  • John Kendrew — John Cowdery Kendrew. Sir John Cowdery Kendrew (* 24. März 1917 in Oxford; † 23. August 1997 in Cambridge) war ein britischer Biochemiker und Molekularbiologe. Er erhielt 1962 gemeinsam mit Max Ferdinand Perutz den Nobelpreis für Chemie. Sein… …   Deutsch Wikipedia

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