Dam , Carl Peter Henrik
(1895–1976) Danish biochemist
Dam was born in Copenhagen and educated at the polytechnic and the university there, obtaining his doctorate in 1934. He taught at the university from 1923 until 1941, when – although stranded in America because of the war – he was appointed professor of biochemistry at the Copenhagen Polytechnic. From 1956 until 1963 Dam served as director of the Biochemical Division of the Danish Fat Research Institute.
From 1928 to 1930 Dam worked on the problem of cholesterol metabolism in chickens. Cholesterol, first analyzed by Heinrich Wieland, is a sterol with an important role in mammalian physiology. It was known that many mammals could readily synthesize it, but it was assumed that chickens lacked this ability. To test this assumption Dam began to rear chickens on a cholesterol-free diet enriched with vitamins A and D.
As it turned out he found that chickens could synthesize cholesterol but, more importantly, he also found that if kept on such a diet for two to three weeks the chickens developed hemorrhages under the skin, and blood removed for examination showed delayed coagulation. Supplementing the diet with fat, vitamin C, and cholesterol made no appreciable difference, so Dam concluded that the condition was due to lack of a hitherto unrecognized factor in the diet.
The missing factor, found to be present in green leaves and pig liver, was designated vitamin K by Dam in 1935 (K being the initial letter of ‘koagulation’, the Scandinavian and German form of the word). Using ether, Dam went on to extract the fat-soluble vitamin K from such sources as alfalfa, and in 1939 succeeded, with Paul Karrer, in isolating it. It was for this work that Dam shared the 1943 Nobel Prize for physiology or medicine withEdward Doisy (1893–1986), the American biochemist who had first synthesized vitamin K in 1940.

Scientists. . 2011.

Look at other dictionaries:

  • Dam, Carl Peter Henrik — Dam , Carl Peter Henrik …   Scientists

  • Dam, (Carl Peter)Henrik — Dam (dăm, däm), (Carl Peter) Henrik. 1895 1976. Danish biochemist. He shared a 1943 Nobel Prize for the discovery of vitamin K. * * * …   Universalium

  • Dam, Carl Peter Henrik — ► (1895 1976) Médico y fisiólogo danés. Fue premio Nobel de Medicina y Fisiología en 1943, compartido con Doisy, por descubrir y aislar la vitamina K …   Enciclopedia Universal

  • Carl Peter Henrik Dam — Henrik Dam Henrik Dam est un biochimiste danois. Il est né le 21 février 1895 à Copenhague et décédé le 17 avril 1975 à Copenhague. Il a réussi à prouver l existence de la vitamine K (1920) et à l isoler à partir de luzerne (1936). Il partage le… …   Wikipédia en Français

  • Henrik Carl Peter Dam — (1895 1976), dansk biokemiker som sammen med amerikaneren Edward Adelbert Doisy modtog nobelprisen i 1943 for opdagelsen af k vitaminet …   Danske encyklopædi

  • Henrik Carl Peter Dam — Henrik Dam Henrik Dam est un biochimiste danois. Il est né le 21 février 1895 à Copenhague et décédé le 17 avril 1975 à Copenhague. Il a réussi à prouver l existence de la vitamine K (1920) et à l isoler à partir de luzerne (1936). Il partage le… …   Wikipédia en Français

  • Medizinnobelpreis 1943: Henrik Carl Peter Dam — Edward Adelbert Doisy —   Der dänische und der amerikanische Biochemiker erhielten den Nobelpreis für die Entdeckung des Vitamins K und dessen chemischer Zusammensetzung.    Biografien   Henrik Carl Peter Dam, * Kopenhagen 21. 2. 1895, ✝ ebenda 17. 4. 1976; ab 1929… …   Universal-Lexikon

  • Dam — Dam, Carl Peter Henrik …   Enciclopedia Universal

  • Henrik Dam — (Full name Carl Peter Henrik Dam) (February 21, 1895 – April 17, 1976) was a Danish biochemist and physiologist.He was awarded the Nobel Prize in Medicine in 1943 for his work in discovering vitamin K and its role in human physiology. His key… …   Wikipedia

  • Henrik Dam — Carl Peter Henrik Dam (* 21. Februar 1895 in Kopenhagen, Dänemark; † 18. April 1976 ebenda) war ein dänischer Physiologe und Biochemiker. Inhaltsverzeichnis 1 Leben 2 Wissenschaftliche Bedeutung 3 …   Deutsch Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”