Chang , Min Chueh
(1908–1991) Chinese–American biologist
Chang, who was born in T'ai-yüan in China, was educated at the Tsinghua University in Peking, and at Cambridge, England, where he obtained his PhD in 1941. He emigrated to America in 1945 and joined the Worcester Foundation in Shrewsbury, Massachusetts, where he subsequently remained. From 1961 he also served as professor of reproductive biology at Boston University.
Chang carried out a number of major research projects from which emerged not only greater understanding of the mechanisms of mammalian fertilization, but also such practical consequences as oral contraceptives and the transplantation of human ova fertilized in vitro (by Robert Edwards and Patrick Steptoe in 1978). In 1951, at the same time as Colin Austin, Chang discovered that a “period of time in the female tract is required for the spermatozoa to acquire their fertilizing capacity,” a phenomenon known later as capacitation. He further demonstrated, in 1957, that there is a decapacitation factor in the seminal fluid, which, although it can be removed by centrifugation, has resisted further attempts at identification.
Chang also made the important advance in 1959 of fertilizing rabbit eggs in vitro and transplanting them into a recipient doe. This was followed in 1964 by comparable work for the first time with rodents. It was also Chang who provided much of the experimental basis for Gregory Pincus's 1953 paper showing that injections of progesterone into rabbits could serve as a contraceptive by inhibiting ovulation.

Scientists. . 2011.

Look at other dictionaries:

  • Min Chueh Chang — Dr. Min Chueh Chang Born October 10, 1908(1908 10 10) Taiyuan, Shanxi, China Died J …   Wikipedia

  • Chueh — may refer to: Wei Chueh (born 1928), Chinese Buddhist monk in Taiwan Min Chueh Chang (1908 – 1991), Chinese American reproductive biologist Luke Chueh (born 1973), artist in lowbrow or pop surrealism art movement Chueh Ming hui (born 1984),… …   Wikipedia

  • Worcester Foundation for Biomedical Research — The Worcester Foundation for Biomedical Research (WFBR) is a non profit biomedical research institute based in Shrewsbury, Massachusetts. The foundation was established as an independent research center under the name Worcester Foundation for… …   Wikipedia

  • Liste der Erfinder — Dies ist eine Liste von Erfindern, die die Welt mit ihren Erfindungen bereichert haben. Ein Erfinder ist jemand, der ein Problem erkannt hat, es gelöst und mindestens einmal damit Erfolg gehabt hat. Er muss nicht der erste gewesen sein; eine… …   Deutsch Wikipedia

  • Liste von Erfindern — Dies ist eine Liste von Erfindern, die die Welt mit ihren Erfindungen bereichert haben. Ein Erfinder ist jemand, der ein Problem erkannt hat, es gelöst und mindestens einmal damit Erfolg gehabt hat. Er muss nicht der erste gewesen sein; eine… …   Deutsch Wikipedia

  • Gregory Goodwin Pincus — Nacimiento 9 de abril de 1903 Woodbine, Nueva Jersey, Estados Unidos Fallecimiento …   Wikipedia Español

  • Asian American — Asian American …   Wikipedia

  • Révolution sexuelle — La révolution sexuelle recouvre les changements substantiels du comportement et des mœurs sexuels intervenus en Occident à la fin des années 1960 et au début des années 1970. Ce mouvement est essentiellement marqué par l émancipation sexuelle des …   Wikipédia en Français

  • Liste bekannter chinesischer US-Amerikaner — In dieser Liste nennt Persönlichkeiten des öffentlichen Lebens, die US amerikanische Staatsbürger sind bzw. waren und chinesische Vorfahren haben. Inhaltsverzeichnis 1 Musiker 2 Künstler, Designer, Architekten 3 Schriftsteller …   Deutsch Wikipedia

  • List of Asian Americans — This page is a list of Asian Americans. Politics*1956 Dalip Singh Saund became the first Asian immigrant elected to the U.S. Congress upon his election to the House of Representatives. *1959 Hiram Fong became the first Asian American elected to… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”