Bloch , Konrad Emil


Bloch , Konrad Emil
(1912–) German–American biochemist
Born in Neisse (now Nysa in Poland), Bloch was educated at the Technical University, Munich, and – after his emigration to America in 1936 – at Columbia University, New York, where he obtained his PhD in 1938. He then taught at Columbia until 1946, when he moved to the University of Chicago, becoming professor of biochemistry there in 1950. In 1954 Bloch accepted the position of Higgins Professor of Chemistry at Harvard, a post he retained until his retirement in 1978.
In 1940 the important radioisotope carbon–14 was discovered by Martin Kamen and Samuel Ruben. Bloch was quick to see that it could be used to determine the biosynthesis of such complex molecules as cholesterol, a basic constituent of animal tissues characterized by four rings of carbon atoms. Thus in 1942, in collaboration with David Rittenberg, Bloch was able to confirm the earlier supposition that cholesterol was partly derived from the two-carbon acetate molecule.
The many steps through which acetate develops into the 27-carbon cholesterol took years of analysis to establish. The breakthrough came in 1953, when Bloch and R. Langdon identified squalene as an intermediate in cholesterol synthesis. Squalene, a terpene with an open chain of 30 carbon atoms, initiates the folding necessary to produce the four rings of cholesterol. For this work Bloch shared the 1964 Nobel Prize for physiology or medicine with Feodor Lynen.

Scientists. . 2011.

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  • Bloch,Konrad Emil — Bloch, Konrad Emil. Born 1912. German born American biochemist. He shared a 1964 Nobel Prize for research on cholesterol and fatty acid metabolism. * * * …   Universalium

  • Bloch, Konrad Emil — ▪ 2001       German born American biochemist (b. Jan. 21, 1912, Neisse, Ger. [now Nysa, Pol.] d. Oct. 15, 2000, Burlington, Mass.), conducted research to determine how the body creates cholesterol, work that earned him a share, together with… …   Universalium

  • Konrad Emil Bloch — Konrad Bloch Pour les articles homonymes, voir Bloch. Konrad Emil Bloch (21 janvier 1912 à Neisse en Allemagne, aujourd hui Nysa en Pologne 15 octobre 2000) était un biochimiste allemand. Biographie Il étudia la chimie à la Technische Hochschule… …   Wikipédia en Français

  • Konrad Emil Bloch — Gedenktafel in Neisse Konrad Emil Bloch (* 21. Januar 1912 in Neisse; † 15. Oktober 2000 in Burlington (Massachusetts)) war ein deutscher Biochemiker und Nobelpreisträger. Leben Konrad Bloch, Sohn von Fritz Bloch und Henna (geborene Striemer),… …   Deutsch Wikipedia

  • Konrad Emil Bloch — (b. January 21 1912 ndash; October 15 2000) was a German American biochemist. Bloch received Nobel Prize in Medicine or Physiology in 1964 (joint with Feodor Lynen) for discoveries concerning the mechanism and regulation of the cholesterol and… …   Wikipedia

  • Bloch, Konrad E. — ▪ American biochemist in full  Konrad Emil Bloch  born January 21, 1912, Neisse, Germany [now Nysa, Poland] died October 15, 2000, Burlington, Massachusetts, U.S.       German born American biochemist who shared the 1964 Nobel Prize for… …   Universalium

  • Konrad Bloch — Bloch , Konrad Emil …   Scientists

  • Konrad E. Bloch — Konrad Bloch Pour les articles homonymes, voir Bloch. Konrad Emil Bloch (21 janvier 1912 à Neisse en Allemagne, aujourd hui Nysa en Pologne 15 octobre 2000) était un biochimiste allemand. Biographie Il étudia la chimie à la Technische Hochschule… …   Wikipédia en Français

  • Konrad Bloch — Pour les articles homonymes, voir Bloch. Konrad Bloch Konrad Emil Bloch (21 janvier 1912 à Neisse en Allemagne, aujourd hui Nysa en …   Wikipédia en Français

  • Konrad Bloch — Placa de Konrad Bloch. Konrad Emil Bloch (21 de enero de 1912 15 de octubre de 2000), científico. Nació en Neisse, Alemania, que actualmente es la ciudad de Nysa (Polonia). Estudia Química en la Escuela Técnica Superior de Múnich, especiali …   Wikipedia Español


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