Bergström , Sune
(1916–) Swedish biochemist
Bergström was born in Stockholm and educated at the Karolinska Institute there, where he obtained his MD in 1943. In 1947 he was appointed to the chair of biochemistry at Lund. In 1958 he moved to a comparable position at the Karolinska Institute, which he left in 1981.
In the 1930s Ulf von Euler found an active substance in human semen capable of lowering blood pressure and causing muscle tissue to contract. He named it prostaglandin on the assumption that it came from the prostate gland. It soon became clear that there was not one such substance but a good many closely related ones with a variety of important physiological roles, but as they were produced in small quantities and rapidly broken down by enzymatic action, they proved to be very difficult to isolate and analyze. From 100 kilograms of rams' seminal vesicles, Bergström was able to extract a minute dose. To his surprise, however, he found the prostaglandin “extraordinarily active in virtually non-existent doses.”
In the 1950s Bergström succeeded in extracting the prostaglandins referred to as PGD2, PGE2, and PGF2. He went on to demonstrate that they were derived from arachidonic acid (C20H36O2), a fatty acid present in the adrenal gland, liver, and brain. Bergström's discovery opened up the study of prostaglandins by allowing them to be produced in the laboratory. For his pioneering work in this field he shared the 1982 Nobel Prize for physiology or medicine with John Vane and Bengt Samuelsson.

Scientists. . 2011.

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  • Bergstrom, Sune Karl — ▪ 2005       Swedish biochemist (b. Jan. 10, 1916, Stockholm, Swed. d. Aug. 15, 2004, Stockholm), laid the groundwork for chemical research on prostaglandins, an important group of natural hormonelike substances that affect blood pressure, body… …   Universalium

  • Bergström, Sune K. — ▪ Swedish biochemist born January 10, 1916, Stockholm, Sweden died August 15, 2004, Stockholm       Swedish biochemist, corecipient with fellow Swede Bengt Ingemar Samuelsson (Samuelsson, Bengt Ingemar) and Englishman John Robert Vane (Vane, Sir… …   Universalium

  • Bergström, Sune K. — ► (n. 1916) Bioquímico sueco. Fue premio Nobel de Medicina y Fisiología en 1982, compartido con B. I. Samuelsson y J. R. Vane, por sus descubrimientos en relación con las prostaglandinas y sustancias afines biológicamente activas …   Enciclopedia Universal

  • Bergstrom — Bergström , Sune …   Scientists

  • Sune K. Bergström — Sune Karl Bergström (* 10. Januar 1916 in Stockholm; † 15. August 2004 ebenda) war ein schwedischer Biochemiker. Er erhielt 1982 gemeinsam mit Bengt Ingemar Samuelsson und Sir John Robert Vane den Nobelpreis für Medizin und Physiologie. Offiziell …   Deutsch Wikipedia

  • Sune Karl Bergström — (* 10. Januar 1916 in Stockholm; † 15. August 2004 ebenda) war ein schwedischer Biochemiker. Er erhielt 1982 gemeinsam mit Bengt Ingemar Samuelsson und Sir John Robert Vane den Nobelpreis für Medizin und Physiologie. Offiziell wurden sie geehrt… …   Deutsch Wikipedia

  • Sune Bergström — Sune Karl Bergström (* 10. Januar 1916 in Stockholm; † 15. August 2004 ebenda) war ein schwedischer Biochemiker. 1972 wurde er mit einem Gairdner Foundation International Award ausgezeichnet. Er erhielt gemeinsam mit Bengt Ingemar Samuels …   Deutsch Wikipedia

  • Sune Karl Bergström — Nacimiento …   Wikipedia Español

  • Sune Bergstrom — Sune Bergström Pour les articles homonymes, voir Bergström. Sune Karl Bergström (10 janvier 1916 à Stockholm – 15 août 2004) était un biochimiste suédois. Il a obtenu en 1977, un Prix Lasker et 1982 le prix Nobel de physiologie ou médecine, qu il …   Wikipédia en Français

  • Sune K. Bergström — Sune Bergström Pour les articles homonymes, voir Bergström. Sune Karl Bergström (10 janvier 1916 à Stockholm – 15 août 2004) était un biochimiste suédois. Il a obtenu en 1977, un Prix Lasker et 1982 le prix Nobel de physiologie ou médecine, qu il …   Wikipédia en Français

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