Adrian , Edgar Douglas
Adrian , Edgar Douglas, Baron Adrian of Cambridge
(1889–1977) British neurophysiologist
Adrian, a lawyer's son, was born in London and studied at Cambridge University and St. Bartholomew's Hospital, London, where he obtained his MD in 1915. He returned to Cambridge in 1919, was appointed professor of physiology in 1937, and became the master of Trinity College, Cambridge, in 1951, an office he retained until his retirement in 1965. He was raised to the British peerage in 1955.
Adrian's greatest contribution to neurophysiology was his work on the nerve impulse. When he began it was known that nerves transmit nerve impulses as signals, but knowledge of the frequency and control of such impulses was minimal. The first insight into this process came from Adrian's colleague Keith Lucas, who demonstrated in 1905 that the impulse obeyed the ‘all-or-none’ law. This asserted that below a certain threshold of stimulation a nerve does not respond. However, once the threshold is reached the nerve continues to respond by a fixed amount however much the stimulation increases. Thus, increased stimulation, although it stimulates more fibers, does not affect the magnitude of the signal itself.
It was not until 1925 that Adrian advanced beyond this position. By painstaking surgical techniques he succeeded in separating individual nerve fibers and amplifying and recording the small action potentials in these fibers. By studying the effect of stretching the sternocutaneous muscle of the frog, Adrian demonstrated how the nerve, even though it transmits an impulse of fixed strength, can still convey a complex message. He found that as the extension increased so did the frequency of the nerve impulse, rising from 10 to 50 impulses per second. Thus, he concluded that the message is conveyed by changes in the frequency of the discharge. For this work Adrian shared the 1932 Nobel Prize for physiology or medicine with Charles Sherrington.

Scientists. . 2011.

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  • Adrian, Edgar Douglas — ► (1889 1977) Fisiólogo británico. Fue premio Nobel de Medicina y Fisiología en 1932, compartido con sir Charles Scott Sherrington, por sus trabajos sobre el funcionalismo neuronal. * * * post. 1o barón Adrian de Cambridge (30 nov. 1889, Londres …   Enciclopedia Universal

  • Adrian, Edgar Douglas — later 1st Baron Adrian of Cambridge born Nov. 30, 1889, London, Eng. died Aug. 4, 1977, London British electrophysiologist. He amplified electrical potential variations in nerve impulses from sense organs to record ever smaller changes,… …   Universalium

  • Adrian, Edgar Douglas Adrian, 1st Baron — ▪ British electrophysiologist born Nov. 30, 1889, London, Eng. died Aug. 4, 1977, Cambridge  British electrophysiologist who with Sir Charles Sherrington (Sherrington, Sir Charles Scott) won the Nobel Prize for Physiology or Medicine in 1932 for… …   Universalium

  • Edgar Douglas Adrian — Edgar Douglas Adrian, 1. Baron Adrian OM (* 30. November 1889 in London; † 4. August 1977 in Cambridge) war ein britischer Anatom und Physiologe. Für seine Entdeckungen auf dem Gebiet der Funktionen der Neuronen erhielt er 1932 gemeinsam mit… …   Deutsch Wikipedia

  • Edgar Douglas Adrian — Pour les articles homonymes, voir Edgar et Adrian. Edgar Douglas Adrian Naissance 30 novembre 1889 Hampstead, Royaume Uni Décès 4  …   Wikipédia en Français

  • Edgar Douglas Adrian — Nacimiento 30 de noviembre de 1889 Hampstead, Londres, Inglaterra Fallecimiento 4 de agosto de 1977 (87 años) Cambridge, Cambridgeshire Nacionali …   Wikipedia Español

  • Edgar Douglas Adrian — (n. Londres, 30 de noviembre de 1889 †, Cambridge, 4 de agosto de 1977). Fisiólogo inglés. Estudió en la Westminster School y ciencias naturales en el Trinity College de Cambridge, licenciándose en medicina en 1915. Durante la I Guerra Mundial… …   Enciclopedia Universal

  • Edgar Douglas Adrian — noun English physiologist who conducted research into the function of neurons; 1st baron of Cambridge (1889 1997) • Syn: ↑Adrian, ↑Baron Adrian • Instance Hypernyms: ↑physiologist …   Useful english dictionary

  • Medizinnobelpreis 1932: Edgar Douglas Adrian — Charles Scott Sherrington —   Die beiden britischen Physiologen erhielten den Nobelpreis für »ihre Entdeckungen auf dem Gebiet der Funktionen der Neuronen«.    Biografien   Lord Edgar Douglas Adrian, * London 30. 11. 1889, ✝ Cambridge 4. 8. 1977; 1911 14 physiologische… …   Universal-Lexikon

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