Milstein , César
(1927–) British molecular biologist
Milstein was born at Bahia Blanca in Argentina and attended the University of Buenos Aires, receiving his degree in 1952 and his doctorate in 1957. Three years later he was granted a PhD by Cambridge University. Milstein returned to his native Argentina in 1961 to head the Molecular Biology Division of the Instituto Nacional de Microbiologiá in Buenos Aires. In 1963 he joined the staff of the Medical Research Council's Laboratory of Molecular Biology in Cambridge and in 1983 he was appointed head of the Division of Protein and Nucleic Acid Chemistry, a post in which he remained until his retirement in 1994.
Milstein is best known for producing the first monoclonal antibodies, using a technique developed at the MRC's Laboratory in collaboration with the German immunologist, George Köhler, and first reported by them in 1975. The pair went on to show how it was possible to manufacture quantities of antibody of any desired specificity employing cultures of so-called ‘hybridoma’ cells. Monoclonal antibodies have found wide-ranging application in biology, medicine, and industry, especially for diagnostic tests and assays. For his part in developing this revolutionary technology, Milstein was awarded the 1984 Nobel Prize for physiology or medicine, which he shared with Köhler and Niels Jerne.

Scientists. . 2011.

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  • MILSTEIN, CESAR — (1927–2002), immunologist and Nobel Prize laureate in medicine. Milstein was born in Bahia Blanca, Argentina. He studied at the University of Buenos Aires and received his doctorate from Cambridge University in 1960. From 1961 to 1963, when he… …   Encyclopedia of Judaism

  • Milstein, César — born Oct. 8, 1927, Bahía Blanca, Arg. died March 24, 2002, Cambridge, Cambridgeshire, Eng. Argentinian born British immunologist. In 1975 Milstein and Georges Köhler (1946–95) fused short lived, highly specific lymphocytes with the cells of a… …   Universalium

  • Milstein, César — ► (1927 2002) Científico argentino. Fue premio Nobel de Medicina y Fisiología en 1984, compartido con Niels Jerne y Georg Koehler, por sus trabajos sobre los sistemas inmunológicos y la producción de anticuerpos. * * * (8 oct. 1927, Bahía Blanca …   Enciclopedia Universal

  • Milstein,Cesar — Mil·stein (mĭlʹstēn ), Cesar. Born 1927. British Argentinian immunologist. He shared a 1984 Nobel Prize for developing a method of producing monoclonal antibodies. * * * …   Universalium

  • Milstein — César …   Scientists

  • Milstein — Milstein, César …   Enciclopedia Universal

  • César Milstein — Born 8 October 1927(1927 10 08) Bahia Blanca, Argentina …   Wikipedia

  • Cesar Milstein — César Milstein (* 8. Oktober 1927 in Bahía Blanca, Argentinien; † 24. März 2002 in Cambridge, England) war ein argentinischer Molekularbiologe. Milstein wuchs als mittlerer von drei Söhnen eines jüdischen Immigranten und einer Lehrerin in… …   Deutsch Wikipedia

  • Cesar Milstein — César Milstein Pour les articles homonymes, voir Milstein. César Milstein (8 octobre 1927 24 mars 2002) est un biochimiste argentin qui passe la plus grande part de sa vie en Grande Bretagne. Son champ majeur de recherche concerne les anticorps,… …   Wikipédia en Français

  • César Milstein — Pour les articles homonymes, voir Milstein. César Milstein. César Milstein (8 octobre 1927 24 mars 2002) est un biochimiste argentin qui passe la plus grande part de sa vie …   Wikipédia en Français

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